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Dichotomy in Hedgehog signaling between human healthy vessel and atherosclerotic plaques

Addressing this gender bias in clinical trial enrollment is a necessary step in promoting equitable representation and thus improving health outcomes

AATD-1 is typically caused by a single-letter mutation in DNA, making it a good candidate for base editing

"Atherosclerosis progression with carnitine supplementation." Nutr Metab (Lond) 2022;19:26

Ueda, Y

Missense mutations in GPCRs can mislead protein folding and post-translational modifications to cause trafficking alterations, in which pharmacological chaperones are applicative therapeutic regimens